Researcher
Eric Verdin
Last updated 2026-05-30· 1 min read
Reviewed by the Ultimate Longevity Bible editorial team. Educational reference — not medical advice. See disclaimer.
Background
Eric Verdin has been President and CEO of the Buck Institute for Research on Aging since 2016. Before that he led the Verdin Lab at the Gladstone Institutes (UCSF affiliate) and trained at the NIH.
Lines of work
- Sirtuin biology: mechanistic work on SIRT3 in mitochondrial acetylation; SIRT1 in metabolic regulation.
- β-hydroxybutyrate as a signalling molecule beyond fuel — HDAC inhibition, NLRP3 inflammasome inhibition; the biology behind ketogenic-diet effects.
- NAD+ metabolism: how NAD+ decline affects sirtuin activity, mitochondrial function.
- Immune aging: T-cell exhaustion and senescence; how immune decline drives systemic aging.
Public communication
A frequent speaker on geroscience translation; advocate for evidence-based caution about consumer longevity products without inhibiting the field’s momentum.
- David Sinclair — Researcher.
- Judith Campisi — Researcher.
- Leonard Guarente — Researcher.
- SIRT6 — Gene.
- Deregulated Nutrient-Sensing — Hallmark.
Related entries
Sirtuins, NAD+ precursors, Ketogenic diet, NLRP3 inflammasome.
References
- Newman, J. C. & Verdin, E. β-Hydroxybutyrate: a signaling metabolite. Annu. Rev. Nutr. 37, 51–76 (2017).