Start here

Welcome to Ultimate Longevity Bible — a research-grounded encyclopedia of longevity science. This page is a 5-minute orientation: how the site is structured, what to read first, and how to use it as a reference rather than a recipe book.

How the site is organised

Content sits in 18 categories. Most cross-link to each other extensively; you can usually start anywhere and follow related links to where you need to be.

• Foundations— start here if you’re new:
  • Hallmarks of aging — the twelve biological processes underlying aging.
  • Healthspan vs lifespan — why "living longer" isn’t the goal.
  • Geroscience hypothesis — the field’s organising premise.
  • Biological vs chronological age — what aging clocks measure.
• What you can do about it:
  • Exercise — the single highest-leverage modifiable factor.
  • Sleep — foundational.
  • Mediterranean diet — the most-evidence-backed dietary pattern.
  • Statins and apoB — modern lipidology.
  • GLP-1 agonists — the most consequential new drug class.
• What to measure: walk through apoB, HbA1c, CAC score, VO2max, grip strength.

By age decade

• In your 30s— foundation building.
• In your 40s— the highest-leverage decade.
• In your 50s— act before midlife inflection points compound.
• In your 60s— preserve function and reserve.
• In your 70s and beyond— emphasis shifts to maintenance and avoiding falls.

By sex

• For women— cycle, perimenopause, menopause, hormone-therapy considerations.
• For men— lipids, testosterone, prostate, screening priorities.

How to read this site

Treat every page as a synthesis of current published evidence with its remaining uncertainty, not as a prescription. Specific drug and supplement recommendations require individual clinician input. Where we use evidence badges, "RCT" means strong randomised-trial support; "observational" means cohort data; "preclinical" means animal or in-vitro work only.

For deeper technical reading, every page links to primary references in the frontmatter (visible at the end of the body).

Useful indexes

• Full sitemap— every URL on the site.
• Glossary— A–Z list of all entries.
• /llms.txt and /llms-full.txt— LLM ingestion files.
• /ai.txt— explicit AI-crawler policy.