Researchers

Aubrey de Grey

Gerontologist and architect of the SENS engineering-style damage-repair framework. Founded SENS Research Foundation; now president of the LEV (Longevity Escape Velocity) Foundation.

Brian Kennedy

NUS Singapore geroscientist working on rapamycin, alpha-ketoglutarate, and combination longevity interventions. Former president of the Buck Institute.

Bryan Johnson

Entrepreneur (Braintree founder) running Project Blueprint — a public, heavily-instrumented self-experiment in maximally aggressive lifestyle and intervention stacks for longevity. Famous and contested.

Carlos López-Otín

University of Oviedo biochemist and first author of the 'Hallmarks of Aging' Cell papers that organised the modern conceptual framework of geroscience.

Cynthia Kenyon

Discovered that a single-gene mutation can double lifespan in C. elegans — the foundational insight that aging is regulated by signalling pathways. Now VP of Aging Research at Calico.

Daniel Belsky

Columbia epidemiologist who developed DunedinPACE — a single-timepoint estimator of the rate of biological aging.

David Sinclair

Harvard Medical School geneticist working on sirtuin biology, NAD+ metabolism, and epigenetic reprogramming. One of the most publicly visible — and most contested — figures in modern geroscience.

Eric Verdin

President and CEO of the Buck Institute for Research on Aging. Works on sirtuins, NAD+ metabolism, β-hydroxybutyrate signalling, and immune-aging.

George Church

Harvard Medical School geneticist whose lab co-founded multiple longevity and synthetic biology companies. Pioneer of cheap whole-genome sequencing and aggressive gene-therapy approaches to aging.

Irina & Michael Conboy

UC Berkeley husband-and-wife team whose heterochronic-parabiosis work re-launched interest in young-blood rejuvenation, then re-framed the field by demonstrating that 'old-blood dilution' may matter more than 'young-blood addition'.

James Kirkland

Mayo Clinic geriatrician whose lab discovered the first senolytic combinations and ran the first human senolytic trials.

João Pedro de Magalhães

University of Birmingham (formerly Liverpool) biogerontologist and curator of the most-used aging-research database (HAGR/GenAge). Works on comparative genomics of long-lived species and AI for drug discovery.

Judith Campisi

Pioneering senescence biologist whose work defined the SASP and reframed senescent cells as a tractable target in age-related disease.

Leonard Guarente

MIT geneticist who discovered the sirtuin family of NAD+-dependent enzymes and their role in lifespan regulation. Co-founder of Elysium Health.

Linda Partridge

UCL geneticist who has shaped the field of evolutionary biology of aging. Director emerita of the Max Planck Institute for Biology of Ageing in Cologne.

Maria Blasco

Director of the Spanish National Cancer Research Centre (CNIO). Telomere and telomerase biology; AAV-TERT gene therapy in mice.

Mark Mattson

Former chief of the Laboratory of Neurosciences at the National Institute on Aging. Pioneered intermittent fasting research and brain-energy resilience as protection against neurodegeneration.

Matt Kaeberlein

Geroscientist focused on rapamycin/mTOR biology and translational geroscience. Lead investigator of the Dog Aging Project; founder of Optispan Health.

Matthew Walker

UC Berkeley neuroscientist and director of the Center for Human Sleep Science. Author of 'Why We Sleep' and the most prominent public voice on sleep science.

Morgan Levine

Biostatistician and gerontologist who developed PhenoAge and DNAm-PhenoAge — biological-age clocks calibrated against clinical biomarkers and mortality.

Nir Barzilai

Director of the Institute for Aging Research at Albert Einstein College of Medicine. Lead investigator of the TAME trial of metformin in non-diabetic older adults.

Peter Attia

Physician, writer, and podcaster who has become the most influential public voice on longevity-oriented preventive medicine. Author of Outlive (2023).

Rich Miller

University of Michigan geroscientist and one of the three NIA Interventions Testing Program site PIs. The 'gold-standard' geroscientist for rigorous mammalian lifespan-intervention testing.

Satchin Panda

Salk Institute biologist whose lab introduced and popularised time-restricted eating as a translational application of circadian biology.

Shinya Yamanaka

Kyoto University stem-cell biologist who discovered induced pluripotent stem cells (iPSC), winning the 2012 Nobel Prize in Physiology or Medicine. The named author of 'Yamanaka factors' (Oct4, Sox2, Klf4, c-Myc).

Steve Horvath

Created the first multi-tissue epigenetic clock from DNA methylation patterns — now the field's most-used biological-age estimator.

Tony Wyss-Coray

Stanford neuroscientist whose parabiosis and young-plasma studies showed that systemic factors influence brain aging — and that some cognitive aging may be reversible.

Vadim Gladyshev

Harvard Medical School biologist developing pan-mammalian molecular clocks and rejuvenation assays across species. Director of redox medicine research at Brigham & Women's.

Valter Longo

USC gerontologist focused on fasting, protein restriction, and the fasting-mimicking diet. Developer of the ProLon FMD protocol.

Vera Gorbunova & Andrei Seluanov

University of Rochester husband-and-wife team studying the biology of long-lived rodents (naked mole-rat, blind mole-rat, beaver) to identify natural mechanisms of cancer resistance and longevity.